Nano-Bio Interfaces

We use micropatterned substrates to investigate different cell metrics. In particular we utilize micropatterned substrates of various geometric constraints to dictate the phenotype of cultured kidney podocytes and we use PDMS pillars to investigate the mechanical traction forces in epithelial cells. 

A biomimetic gelatin-based platform elicits a pro-differentiation effect on podocytes through mechanotransduction

Cells test substrate rigidity by local contractions on submicrometer pillars